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We examine whether a daily mindfulness practice can help people cope better with quarantine during the COVID-19 outbreak. We conducted a study in Wuhan, China between February 20th, 2020 and March 2nd, 2020. We randomly assigned participants to either a daily mindfulness practice or a daily mind-wandering practice. Mindfulness reduced daily anxiety. In addition, the sleep duration of participants in the mindfulness condition was less impacted by the increase of infections in the community compared with participants in the control condition. As the COVID-19 pandemic is ongoing and the number of cases reported in the community increase, our findings offer an evidence-based practice that may help people cope with news about an outbreak in the community.